Linked Life Data

20201423

Source:http://linkedlifedata.com/resource/pubmed/id/20201423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-3-5
pubmed:abstractText
Pyrene excimer nucleic acid probes are novel molecular probes that integrate the unique optical properties of pyrene excimer with excellent recognition capability of nucleic acids. Pyrene has the property of forming excimer that has a large Stokes shift and long fluorescence lifetime. Nucleic acid probes, like aptamers and molecular beacons, can directly bind to target molecules with a high selectivity and affinity. Possessing these outstanding characteristics of pyrene excimer and nucleic acid probes, pyrene excimer nucleic acid probes can be effectively used in detection of biomolecules, study of protein-DNA interactions, and investigation of enzymatic processes in complex biological systems. In this review, we will discuss the optical properties of pyrene excimer and summarize recent progresses on pyrene excimer signaling nucleic acid probes for the signaling of biomolecules and their interactions in complex biological samples.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1550-7033
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
495-504
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Pyrene excimer nucleic acid probes for biomolecule signaling.
pubmed:affiliation
Department of Chemical Biology, College of Chemistry and Chemical Engineering, Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen 361005, China.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't