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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1978-2-18
|
| pubmed:abstractText |
Using a quench-flow technique, the initial velocity of Ca2+ accumulation by isolated cardiac sarcoplasmic reticulum was estimated at free Ca2+ ion concentrations in the range encountered in the myoplasm during the cardiac contraction cycle. With cardiac microsomes exhibiting a Ca2+ accumulative capacity of 25.6 nmol Ca2+/mg protein, initial rates were found to increase from 3.7 to 33.4 nmol Ca2+/mg protein/sec, when the free Ca2+ ion concentration was raised from 0.2 to 18.0 muM. Preincubation of the cardiac microsomes with a party purified soluble cardiac protein kinase, MgATP, and cAMP led to a significant increase in the initial Ca2+ accumulation rate.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0363-5872
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
199-204
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:201981-Animals,
pubmed-meshheading:201981-Biological Transport, Active,
pubmed-meshheading:201981-Calcium,
pubmed-meshheading:201981-Cyclic AMP,
pubmed-meshheading:201981-Kinetics,
pubmed-meshheading:201981-Membranes,
pubmed-meshheading:201981-Microsomes,
pubmed-meshheading:201981-Myocardial Contraction,
pubmed-meshheading:201981-Myocardium,
pubmed-meshheading:201981-Protein Kinases,
pubmed-meshheading:201981-Rabbits,
pubmed-meshheading:201981-Sarcoplasmic Reticulum
|
| pubmed:articleTitle |
Quench-flow measurements of initial rates of Ca2+ accumulation by isolated cardiac sarcoplasmic reticulum.
|
| pubmed:publicationType |
Journal Article
|