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rdf:type |
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lifeskim:mentions |
umls-concept:C0001924,
umls-concept:C0017262,
umls-concept:C0078056,
umls-concept:C0079904,
umls-concept:C0080298,
umls-concept:C0087163,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C1280500,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2010-3-26
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pubmed:abstractText |
Fatty acid-bearing albumin [FA(+) albumin] exerts more deleterious effects in tubular cells than albumin alone. We investigated the effect of FA(+) albumin on the vascular cell adhesion molecule-1 (VCAM-1) expression and elucidated the underlying signaling pathways. We further examined the effect of L-carnitine, since it was known to modulate intracellular fatty acid concentration.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Albumins,
http://linkedlifedata.com/resource/pubmed/chemical/CSK tyrosine-protein kinase,
http://linkedlifedata.com/resource/pubmed/chemical/Carnitine,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/I-kappa B Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappaB inhibitor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Cell Adhesion Molecule-1,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin B Complex
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0143
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
72-84
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:20197690-Albumins,
pubmed-meshheading:20197690-Carnitine,
pubmed-meshheading:20197690-Cell Line,
pubmed-meshheading:20197690-Fatty Acids,
pubmed-meshheading:20197690-Gene Expression,
pubmed-meshheading:20197690-Humans,
pubmed-meshheading:20197690-I-kappa B Proteins,
pubmed-meshheading:20197690-Kidney Diseases,
pubmed-meshheading:20197690-Kidney Tubules, Proximal,
pubmed-meshheading:20197690-Lipid Metabolism,
pubmed-meshheading:20197690-NF-kappa B,
pubmed-meshheading:20197690-Protein-Tyrosine Kinases,
pubmed-meshheading:20197690-RNA, Messenger,
pubmed-meshheading:20197690-Signal Transduction,
pubmed-meshheading:20197690-Transcription Factor AP-1,
pubmed-meshheading:20197690-Vascular Cell Adhesion Molecule-1,
pubmed-meshheading:20197690-Vitamin B Complex
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pubmed:year |
2010
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pubmed:articleTitle |
Fatty acid-bearing albumin induces VCAM-1 expression through c-Src kinase-AP-1/NF-kB pathways: effect of L-carnitine.
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pubmed:affiliation |
Department of Internal Medicine, Asan Institute for Life Sciences, College of Medicine, University of Ulsan, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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