|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2010-3-26
|
|
pubmed:abstractText |
Lgr5 is a member of the G protein receptor super-family and was shown recently to be a stem cell marker for cells with intestinal differentiation. Its over-expression has been demonstrated in hepatocellular, basal cell carcinoma, and ovarian cancers but the underlying mechanisms are poorly understood. The aim of this study was to investigate if Lgr5 over-expression was correlated with human colorectal carcinogenesis and its potential correlation with beta-catenin.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1432-1262
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
583-90
|
|
pubmed:meshHeading |
pubmed-meshheading:20195621-Adenoma,
pubmed-meshheading:20195621-Adult,
pubmed-meshheading:20195621-Aged,
pubmed-meshheading:20195621-Aged, 80 and over,
pubmed-meshheading:20195621-Colorectal Neoplasms,
pubmed-meshheading:20195621-Female,
pubmed-meshheading:20195621-Humans,
pubmed-meshheading:20195621-Immunohistochemistry,
pubmed-meshheading:20195621-Intestinal Mucosa,
pubmed-meshheading:20195621-Male,
pubmed-meshheading:20195621-Middle Aged,
pubmed-meshheading:20195621-Neoplasm Invasiveness,
pubmed-meshheading:20195621-Receptors, G-Protein-Coupled,
pubmed-meshheading:20195621-Tumor Suppressor Protein p53,
pubmed-meshheading:20195621-beta Catenin
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with beta-catenin.
|
|
pubmed:affiliation |
Department of Pathology, Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, People's Republic of China.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
