Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-5-28
|
pubmed:abstractText |
Blood pressure was continuously recorded for 24 h in 31 non-insulin-dependent diabetic men with borderline, mild, or moderate systolic and/or diastolic hypertension. A 2-h oral glucose tolerance test was also performed with blood glucose, serum insulin and C-peptide determination at 30-min intervals. Significant correlations were found between fasting and post-glucose integrated area of blood glucose, insulin and C-peptide concentrations versus blood pressure measures. Total insulin area appeared to correlate significantly with diastolic measures [casual, daytime, night-time, mean computational (mesor), hyperbaric impact and percent time elevation], mean blood pressure, and mesor and hyperbaric impact systolic measures. It is concluded that the more accurate assessment of the circadian pattern of blood pressure by a chronobiological procedure allowed the existence of close correlations between metabolic and blood pressure measures to be established, confirming the importance of hyperinsulinaemia in the pathophysiology of arterial hypertension.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-0605
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
50-4
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2019315-Blood Glucose,
pubmed-meshheading:2019315-Blood Pressure,
pubmed-meshheading:2019315-C-Peptide,
pubmed-meshheading:2019315-Diabetes Mellitus, Type 2,
pubmed-meshheading:2019315-Fasting,
pubmed-meshheading:2019315-Glucose Tolerance Test,
pubmed-meshheading:2019315-Humans,
pubmed-meshheading:2019315-Hyperinsulinism,
pubmed-meshheading:2019315-Hypertension,
pubmed-meshheading:2019315-Insulin,
pubmed-meshheading:2019315-Middle Aged
|
pubmed:articleTitle |
Hyperinsulinaemia in hypertension and diabetes mellitus: a chronobiological approach.
|
pubmed:affiliation |
Institute of Internal Medicine, Chieti University, Italy.
|
pubmed:publicationType |
Journal Article
|