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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-7-16
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pubmed:abstractText |
Structural adaptation of the vessel wall in response to sustained alterations in haemodynamic forces is known as vascular remodelling. Detailed knowledge on the mechanism underlying this vascular response is limited, and we aimed to study the function of Nur77 in smooth muscle cells (SMCs) in arterial remodelling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 13,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp13 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp9 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Nr4a1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Receptor Subfamily 4...,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoconstrictor Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1755-3245
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
561-8
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pubmed:meshHeading |
pubmed-meshheading:20189954-Adaptation, Physiological,
pubmed-meshheading:20189954-Animals,
pubmed-meshheading:20189954-Blood Pressure,
pubmed-meshheading:20189954-Carotid Arteries,
pubmed-meshheading:20189954-Carotid Artery Diseases,
pubmed-meshheading:20189954-Disease Models, Animal,
pubmed-meshheading:20189954-Dose-Response Relationship, Drug,
pubmed-meshheading:20189954-Down-Regulation,
pubmed-meshheading:20189954-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20189954-Hemodynamics,
pubmed-meshheading:20189954-Macrophages,
pubmed-meshheading:20189954-Matrix Metalloproteinase 13,
pubmed-meshheading:20189954-Matrix Metalloproteinase 2,
pubmed-meshheading:20189954-Matrix Metalloproteinase 9,
pubmed-meshheading:20189954-Matrix Metalloproteinases,
pubmed-meshheading:20189954-Mice,
pubmed-meshheading:20189954-Mice, Transgenic,
pubmed-meshheading:20189954-Nuclear Receptor Subfamily 4, Group A, Member 1,
pubmed-meshheading:20189954-RNA, Messenger,
pubmed-meshheading:20189954-Regional Blood Flow,
pubmed-meshheading:20189954-Time Factors,
pubmed-meshheading:20189954-Vasoconstriction,
pubmed-meshheading:20189954-Vasoconstrictor Agents,
pubmed-meshheading:20189954-Vasodilation,
pubmed-meshheading:20189954-Vasodilator Agents
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pubmed:year |
2010
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pubmed:articleTitle |
Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels.
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pubmed:affiliation |
Department of Medical Biochemistry, Academic Medical Center K1-113, University of Amsterdam, Meibergdreef 15, Amsterdam 1105 AZ, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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