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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-4-5
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pubmed:abstractText |
Transforming growth factor beta (TGF-beta) signaling via Smads plays a central role in carcinogenesis. Bmp and activin membrane-bound inhibitor (BAMBI) was initially described as a pseudoreceptor antagonizing TGF-beta receptor activation, thus impairing signaling. Here we wanted to estimate the role of BAMBI in ovarian cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BAMBI protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SMAD2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/SMAD3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Smad2 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1095-6859
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pubmed:author |
pubmed-author:AlfanzAngelaA,
pubmed-author:BraicuElena-IoanaEI,
pubmed-author:GregorWolfgangW,
pubmed-author:GugerellAlfredA,
pubmed-author:HorvatReinhardR,
pubmed-author:KrainerMichaelM,
pubmed-author:MikulitsWolfgangW,
pubmed-author:PetzMichaelaM,
pubmed-author:PilsDietmarD,
pubmed-author:SehouliJalidJ,
pubmed-author:WittingerMichaelM,
pubmed-author:ZeillingerRobertR
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pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-97
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pubmed:dateRevised |
2011-4-6
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pubmed:meshHeading |
pubmed-meshheading:20189233-Adult,
pubmed-meshheading:20189233-Aged,
pubmed-meshheading:20189233-Aged, 80 and over,
pubmed-meshheading:20189233-Cell Line, Tumor,
pubmed-meshheading:20189233-Cell Nucleus,
pubmed-meshheading:20189233-Female,
pubmed-meshheading:20189233-Humans,
pubmed-meshheading:20189233-Membrane Proteins,
pubmed-meshheading:20189233-Middle Aged,
pubmed-meshheading:20189233-Ovarian Neoplasms,
pubmed-meshheading:20189233-Phosphorylation,
pubmed-meshheading:20189233-RNA, Messenger,
pubmed-meshheading:20189233-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20189233-Signal Transduction,
pubmed-meshheading:20189233-Smad2 Protein,
pubmed-meshheading:20189233-Smad3 Protein,
pubmed-meshheading:20189233-Transforming Growth Factor beta,
pubmed-meshheading:20189233-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
BAMBI is overexpressed in ovarian cancer and co-translocates with Smads into the nucleus upon TGF-beta treatment.
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pubmed:affiliation |
Department of Internal Medicine I, Division of Oncology, Medical University of Vienna, Austria. dietmar.pils@univie.ac.at
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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