rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2010-6-21
|
pubmed:abstractText |
Krüppel-like factor 8 (KLF8) plays an important role in oncogenic transformation and is highly overexpressed in several types of human cancer. We investigated the expression of KLF8 in renal cell carcinoma (RCC) tissues and the role of small interference RNA targeting KLF8 on growth, cell cycle, and apoptosis of human renal carcinoma cell line 786-0 in vitro and in vivo.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1432-1335
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
136
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1255-65
|
pubmed:meshHeading |
pubmed-meshheading:20182889-Adult,
pubmed-meshheading:20182889-Aged,
pubmed-meshheading:20182889-Aged, 80 and over,
pubmed-meshheading:20182889-Animals,
pubmed-meshheading:20182889-Base Sequence,
pubmed-meshheading:20182889-Cell Division,
pubmed-meshheading:20182889-Cell Line, Tumor,
pubmed-meshheading:20182889-DNA Primers,
pubmed-meshheading:20182889-Female,
pubmed-meshheading:20182889-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:20182889-Humans,
pubmed-meshheading:20182889-Immunohistochemistry,
pubmed-meshheading:20182889-Kidney Neoplasms,
pubmed-meshheading:20182889-Male,
pubmed-meshheading:20182889-Mice,
pubmed-meshheading:20182889-Mice, Nude,
pubmed-meshheading:20182889-Middle Aged,
pubmed-meshheading:20182889-RNA, Messenger,
pubmed-meshheading:20182889-RNA, Small Interfering,
pubmed-meshheading:20182889-Repressor Proteins,
pubmed-meshheading:20182889-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20182889-Transfection,
pubmed-meshheading:20182889-Tumor Markers, Biological
|
pubmed:year |
2010
|
pubmed:articleTitle |
Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo.
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pubmed:affiliation |
Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi, People's Republic of China.
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pubmed:publicationType |
Journal Article
|