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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-4-26
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pubmed:abstractText |
Pathogenesis studies show that naive CD4 cells are preferentially depleted in lymphoid tissues during HIV infection, and studies of advanced patients suggest levels of naive CD4 cells in blood correlate to total CD4 cells after starting antiretroviral therapy (ARV). We hypothesized that measuring naive CD4 cells in blood in people at earlier stages of disease would identify those at highest risk for poor CD4 reconstitution who may benefit from earlier initiation of ARV.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1944-7884
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-62
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pubmed:dateRevised |
2011-2-25
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pubmed:meshHeading |
pubmed-meshheading:20182359-Adult,
pubmed-meshheading:20182359-Anti-HIV Agents,
pubmed-meshheading:20182359-CD4 Lymphocyte Count,
pubmed-meshheading:20182359-CD4-Positive T-Lymphocytes,
pubmed-meshheading:20182359-Female,
pubmed-meshheading:20182359-HIV Infections,
pubmed-meshheading:20182359-Humans,
pubmed-meshheading:20182359-Male,
pubmed-meshheading:20182359-Prognosis,
pubmed-meshheading:20182359-Treatment Outcome,
pubmed-meshheading:20182359-Viral Load
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pubmed:year |
2010
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pubmed:articleTitle |
Measurement of naive CD4 cells reliably predicts potential for immune reconstitution in HIV.
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pubmed:affiliation |
Department of Medicine, University of Minnesota, MMC 250 516 Delaware Street SE, Minneapolis, MN 55455, USA. schacker@umn.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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