Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-6-10
pubmed:abstractText
The relationship between cerebrovascular impairment and Alzheimer's disease is a controversial debate. An important and topical aspect in clinical research is the attempt to define the role of atherosclerosis and its determinants in the presentation and evolution of dementia. In this article, we discuss the evidence of the interaction between degenerative and vascular mechanisms in the pathogenesis of dementia. Moreover, we present data about the influence of hypertension and dyslipidemia, usually considered among the most important risk factors for atherosclerosis, on the evolution of Alzheimer's disease. The effects of antihypertensive and lipid-lowering drugs on cognitive impairment will be also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1875-8908
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
893-901
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Atherosclerosis in the evolution of Alzheimer's disease: can treatment reduce cognitive decline?
pubmed:affiliation
Department of Neuroscience, Marche Polytechnic University, Ancona, Italy.
pubmed:publicationType
Journal Article, Review