rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
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pubmed:dateCreated |
2010-3-2
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pubmed:abstractText |
Characterization of new anticancer drugs in a few xenograft models derived from established human cancer cell lines frequently results in the discrepancy between preclinical and clinical results. To take the heterogeneity of tumors into consideration more thoroughly, we describe here a preclinical approach that may allow a more rational clinical development of new anticancer drugs.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Benzenesulfonates,
http://linkedlifedata.com/resource/pubmed/chemical/Benzothiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Epothilones,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/bevacizumab,
http://linkedlifedata.com/resource/pubmed/chemical/sagopilone,
http://linkedlifedata.com/resource/pubmed/chemical/sorafenib
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1452-65
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20179216-Animals,
pubmed-meshheading:20179216-Antibodies, Monoclonal,
pubmed-meshheading:20179216-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:20179216-Antineoplastic Agents,
pubmed-meshheading:20179216-Benzenesulfonates,
pubmed-meshheading:20179216-Benzothiazoles,
pubmed-meshheading:20179216-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20179216-Drug Resistance, Neoplasm,
pubmed-meshheading:20179216-Epothilones,
pubmed-meshheading:20179216-Gene Expression Profiling,
pubmed-meshheading:20179216-Humans,
pubmed-meshheading:20179216-Lung Neoplasms,
pubmed-meshheading:20179216-Mice,
pubmed-meshheading:20179216-Pyridines,
pubmed-meshheading:20179216-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20179216-Xenograft Model Antitumor Assays
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pubmed:year |
2010
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pubmed:articleTitle |
Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
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pubmed:affiliation |
Bayer Schering Pharma AG, Global Drug Discovery, Berlin, Germany. stefanie.hammer@bayerhealthcare.com
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pubmed:publicationType |
Journal Article
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