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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-3-12
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pubmed:abstractText |
The original sequencing and annotation of the Caenorhabditis elegans genome along with recent advances in sequencing technology provide an exceptional opportunity for the genomic analysis of wild-type and mutant strains. Using the Illumina Genome Analyzer, we sequenced the entire genome of Rec-1, a strain that alters the distribution of meiotic crossovers without changing the overall frequency. Rec-1 was derived from ethylmethane sulfonate (EMS)-treated strains, one of which had a high level of transposable element mobility. Sequencing of this strain provides an opportunity to examine the consequences on the genome of altering the distribution of meiotic recombination events.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-10778742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-12679551,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-17246286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-17267812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18023126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18204455,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18677319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18701715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18714091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-18974170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-19189945,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-19289596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-19622155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-1978238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-19805298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-2541437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-3609740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-4366476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-492325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-564463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-6806143,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-7510362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-8601478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20178641-9851916
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20178641-Animals,
pubmed-meshheading:20178641-Base Sequence,
pubmed-meshheading:20178641-Caenorhabditis elegans,
pubmed-meshheading:20178641-Comparative Genomic Hybridization,
pubmed-meshheading:20178641-DNA, Helminth,
pubmed-meshheading:20178641-DNA Transposable Elements,
pubmed-meshheading:20178641-Genome, Helminth,
pubmed-meshheading:20178641-Meiosis,
pubmed-meshheading:20178641-Molecular Sequence Data,
pubmed-meshheading:20178641-Mutagenesis, Insertional,
pubmed-meshheading:20178641-Recombination, Genetic,
pubmed-meshheading:20178641-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:20178641-Sequence Analysis, DNA,
pubmed-meshheading:20178641-Software
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pubmed:year |
2010
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pubmed:articleTitle |
Genomic sequence of a mutant strain of Caenorhabditis elegans with an altered recombination pattern.
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pubmed:affiliation |
Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada. ann.rose@ubc.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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