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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-3-22
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pubmed:abstractText |
The Arabidopsis dynamin-related protein 1A (AtDRP1A) is involved in endocytosis and cell plate maturation in Arabidopsis. Unlike dynamin, AtDRP1A does not have any recognized membrane binding or protein-protein interaction domains. We report that GTPase active AtDRP1A purified from Escherichia coli as a fusion to maltose binding protein forms homopolymers visible by negative staining electron microscopy. These polymers interact with protein-free liposomes whose lipid composition mimics that of the inner leaflet of the Arabidopsis plasma membrane, suggesting that lipid-binding may play a role in AtDRP1A function. However, AtDRP1A polymers do not appear to assemble and disassemble in a dynamic fashion and do not have the ability to tubulate liposomes in vitro, suggesting that additional factors or modifications are necessary for AtDRP1A's in vivo function.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-10559860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-10722722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-11242086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-11351070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-11549762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-11584275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-12105222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-12122474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-12427991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-12671086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-15044754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-15133500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-15262989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-15450295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-15923323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-16186251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-16413294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-17170701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-18256049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-18344418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-18978020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-19754444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-7877694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-8798389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-8947047,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-9298808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-9342876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-9346955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-9635431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20171176-9891074
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1090-2104
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
393
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
734-9
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pubmed:dateRevised |
2010-9-30
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pubmed:meshHeading |
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pubmed:year |
2010
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pubmed:articleTitle |
Arabidopsis dynamin-related protein 1A polymers bind, but do not tubulate, liposomes.
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pubmed:affiliation |
Department of Biochemistry, University of Wisconsin - Madison, 433 Babcock Dr., Madison, WI 53706, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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