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rdf:type |
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lifeskim:mentions |
umls-concept:C0014507,
umls-concept:C0026882,
umls-concept:C0121925,
umls-concept:C0205460,
umls-concept:C0332120,
umls-concept:C0449379,
umls-concept:C1280500,
umls-concept:C1514562,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221
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pubmed:issue |
7
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pubmed:dateCreated |
2010-3-3
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pubmed:abstractText |
The connection domain mutation N348I confers resistance to zidovudine (AZT) and is associated with the lamivudine (3TC) mutation M184V. We explored the biochemical and virological influence of N348I in the context of M184V.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1537-6613
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pubmed:author |
pubmed-author:BöniJürgJ,
pubmed-author:BürgisserPhilippeP,
pubmed-author:DemeterLisa MLM,
pubmed-author:EhteshamiMaryamM,
pubmed-author:GötteMatthiasM,
pubmed-author:GünthardHuldrych FHF,
pubmed-author:KlimkaitThomasT,
pubmed-author:LedergerberBrunoB,
pubmed-author:NijhuisMoniqueM,
pubmed-author:SchuurmanRobR,
pubmed-author:Swiss HIV Cohort Study,
pubmed-author:SymonsJoriJ,
pubmed-author:YerlySabineS,
pubmed-author:von WylViktorV
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
201
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1054-62
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pubmed:meshHeading |
pubmed-meshheading:20170373-Cell Line,
pubmed-meshheading:20170373-DNA, Viral,
pubmed-meshheading:20170373-Drug Resistance, Multiple, Viral,
pubmed-meshheading:20170373-Drug Therapy, Combination,
pubmed-meshheading:20170373-HIV Infections,
pubmed-meshheading:20170373-HIV Reverse Transcriptase,
pubmed-meshheading:20170373-HIV-1,
pubmed-meshheading:20170373-Humans,
pubmed-meshheading:20170373-Lamivudine,
pubmed-meshheading:20170373-Mutation,
pubmed-meshheading:20170373-Reverse Transcriptase Inhibitors,
pubmed-meshheading:20170373-Ribonuclease H, Human Immunodeficiency Virus,
pubmed-meshheading:20170373-Selection, Genetic,
pubmed-meshheading:20170373-Statistics, Nonparametric,
pubmed-meshheading:20170373-Zidovudine
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pubmed:year |
2010
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pubmed:articleTitle |
Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase.
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pubmed:affiliation |
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8091 Zurich, Switzerland. huldrych.guenthard@usz.ch
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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