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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1978-2-18
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pubmed:abstractText |
A 37-year-old woman had symptoms of Cushing's disease for two years. Galactorrhea was present. The diagnosis was confirmed by finding intermittently elevated urinary 17-hydroxysteroids, absent circadian rhythm, and elevated plasma ACTH. Plasma prolactin was slightly elevated. Films of the sella turcica were normal. A 9 mm basophilic microadenoma was removed by the transphenoidal approach. Immunocytochemical and electron-microscopic studies showed that the tumor was composed exclusively of ACTH secreting cells. Endocrine re-evaluation one year later revealed normal adrenal function. Serum prolactin had returned to normal. This case provides further evidence that Cushing's disease can be caused by a pituitary microadenoma insufficient in size to deform the sella.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0021-972X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1251-60
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:201660-Adenoma, Basophil,
pubmed-meshheading:201660-Adult,
pubmed-meshheading:201660-Cushing Syndrome,
pubmed-meshheading:201660-Dexamethasone,
pubmed-meshheading:201660-Female,
pubmed-meshheading:201660-Humans,
pubmed-meshheading:201660-Pituitary Neoplasms,
pubmed-meshheading:201660-Prolactin,
pubmed-meshheading:201660-Sella Turcica
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pubmed:year |
1977
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pubmed:articleTitle |
Cure of Cushing's disease by transsphenoidal removal of a microadenoma from a pituitary gland despite a radiographically normal sella turcica.
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pubmed:publicationType |
Journal Article,
Case Reports
|