Source:http://linkedlifedata.com/resource/pubmed/id/20164834
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2010-3-22
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pubmed:abstractText |
Several reports have demonstrated that the efficacy of latanoprost is influenced by the time of dosing. This model-based meta-analysis validates previous findings that evening dosing is superior to morning dosing and predicts the optimal time for dosing, based on the quantitative assessment of baseline and latanoprost-treated 24-h circadian intraocular pressure (IOP) curves. The results confirm the importance of the time of dosing as a factor that influences the extent of reduction in IOP and underline the need to take this factor into consideration in the design of glaucoma trials and therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1532-6535
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-5
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pubmed:meshHeading |
pubmed-meshheading:20164834-Antihypertensive Agents,
pubmed-meshheading:20164834-Circadian Rhythm,
pubmed-meshheading:20164834-Drug Administration Schedule,
pubmed-meshheading:20164834-Glaucoma, Open-Angle,
pubmed-meshheading:20164834-Humans,
pubmed-meshheading:20164834-Intraocular Pressure,
pubmed-meshheading:20164834-Ocular Hypertension,
pubmed-meshheading:20164834-Prostaglandins F, Synthetic
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pubmed:year |
2010
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pubmed:articleTitle |
A model-based meta-analysis of the effect of latanoprost chronotherapy on the circadian intraocular pressure of patients with glaucoma or ocular hypertension.
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pubmed:affiliation |
Department of Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, La Jolla, California, USA. kenneth.luu@pfizer.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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