Source:http://linkedlifedata.com/resource/pubmed/id/20163849
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-4-5
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pubmed:abstractText |
Laminin-5 is required in RAS and NF-kappaB blockade induced tumorigenesis of human squamous cell carcinoma and a marker of invasiveness in cervical lesions. MicroRNA-218 (miR-218) can target laminin-5 beta3 (LAMB3), but suppressed by HPV-16 E6 protein. Therefore, we hypothesized that single nucleotide polymorphisms (SNPs) in pri-miR-218 and LAMB3 may individually and/or jointly contribute to cervical cancer carcinogenesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1095-6859
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
287-90
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pubmed:meshHeading |
pubmed-meshheading:20163849-Case-Control Studies,
pubmed-meshheading:20163849-Cell Adhesion Molecules,
pubmed-meshheading:20163849-China,
pubmed-meshheading:20163849-Female,
pubmed-meshheading:20163849-Genetic Predisposition to Disease,
pubmed-meshheading:20163849-Genotype,
pubmed-meshheading:20163849-Humans,
pubmed-meshheading:20163849-MicroRNAs,
pubmed-meshheading:20163849-Middle Aged,
pubmed-meshheading:20163849-Polymorphism, Single Nucleotide,
pubmed-meshheading:20163849-Uterine Cervical Neoplasms
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pubmed:year |
2010
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pubmed:articleTitle |
Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women.
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pubmed:affiliation |
Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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