rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-17
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pubmed:abstractText |
Glucagon-like peptide-1 (GLP-1) is a proglucagon-derived peptide expressed in the enteroendocrine-L cells of small and large intestine and released in response to meal ingestion. Glucagon-like peptide-1 exerts inhibitory effects on gastrointestinal motility through vagal afferents and central nervous mechanisms; however, no data is available about a direct influence on the gastrointestinal wall. Our aim was to investigate the effects of GLP-1 on the spontaneous and evoked mechanical activity of mouse duodenum and colon and to identify the presence and distribution of GLP-1 receptors (GLP-1R) in the muscle coat.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholinesterase,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon-Like Peptide 1,
http://linkedlifedata.com/resource/pubmed/chemical/Guanethidine,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Nitroarginine,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Sympatholytics,
http://linkedlifedata.com/resource/pubmed/chemical/exendin (9-39),
http://linkedlifedata.com/resource/pubmed/chemical/glucagon-like peptide receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1365-2982
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
664-e203
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pubmed:meshHeading |
pubmed-meshheading:20158614-Acetylcholinesterase,
pubmed-meshheading:20158614-Animals,
pubmed-meshheading:20158614-Enteric Nervous System,
pubmed-meshheading:20158614-Enzyme Inhibitors,
pubmed-meshheading:20158614-Gastrointestinal Motility,
pubmed-meshheading:20158614-Glucagon-Like Peptide 1,
pubmed-meshheading:20158614-Guanethidine,
pubmed-meshheading:20158614-Immunohistochemistry,
pubmed-meshheading:20158614-Male,
pubmed-meshheading:20158614-Mice,
pubmed-meshheading:20158614-Mice, Inbred C57BL,
pubmed-meshheading:20158614-Motor Neurons,
pubmed-meshheading:20158614-Neurons,
pubmed-meshheading:20158614-Nitric Oxide Synthase Type I,
pubmed-meshheading:20158614-Nitroarginine,
pubmed-meshheading:20158614-Peptide Fragments,
pubmed-meshheading:20158614-Peripheral Nervous System,
pubmed-meshheading:20158614-Receptors, Glucagon,
pubmed-meshheading:20158614-Sympatholytics
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pubmed:year |
2010
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pubmed:articleTitle |
Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors.
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pubmed:affiliation |
Dipartimento di Biologia cellulare e dello Sviluppo, Università di Palermo, 90128 Palermo, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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