Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-6-17
pubmed:abstractText
Glucagon-like peptide-1 (GLP-1) is a proglucagon-derived peptide expressed in the enteroendocrine-L cells of small and large intestine and released in response to meal ingestion. Glucagon-like peptide-1 exerts inhibitory effects on gastrointestinal motility through vagal afferents and central nervous mechanisms; however, no data is available about a direct influence on the gastrointestinal wall. Our aim was to investigate the effects of GLP-1 on the spontaneous and evoked mechanical activity of mouse duodenum and colon and to identify the presence and distribution of GLP-1 receptors (GLP-1R) in the muscle coat.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1365-2982
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
664-e203
pubmed:meshHeading
pubmed-meshheading:20158614-Acetylcholinesterase, pubmed-meshheading:20158614-Animals, pubmed-meshheading:20158614-Enteric Nervous System, pubmed-meshheading:20158614-Enzyme Inhibitors, pubmed-meshheading:20158614-Gastrointestinal Motility, pubmed-meshheading:20158614-Glucagon-Like Peptide 1, pubmed-meshheading:20158614-Guanethidine, pubmed-meshheading:20158614-Immunohistochemistry, pubmed-meshheading:20158614-Male, pubmed-meshheading:20158614-Mice, pubmed-meshheading:20158614-Mice, Inbred C57BL, pubmed-meshheading:20158614-Motor Neurons, pubmed-meshheading:20158614-Neurons, pubmed-meshheading:20158614-Nitric Oxide Synthase Type I, pubmed-meshheading:20158614-Nitroarginine, pubmed-meshheading:20158614-Peptide Fragments, pubmed-meshheading:20158614-Peripheral Nervous System, pubmed-meshheading:20158614-Receptors, Glucagon, pubmed-meshheading:20158614-Sympatholytics
pubmed:year
2010
pubmed:articleTitle
Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors.
pubmed:affiliation
Dipartimento di Biologia cellulare e dello Sviluppo, Università di Palermo, 90128 Palermo, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't