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rdf:type |
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lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0007301,
umls-concept:C0016030,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0033684,
umls-concept:C0442805,
umls-concept:C1269955,
umls-concept:C1550315,
umls-concept:C1879547,
umls-concept:C2699153
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pubmed:issue |
5
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pubmed:dateCreated |
2010-5-12
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pubmed:abstractText |
Since fibroblasts in the synovium of patients with rheumatoid arthritis (RA) express the serine proteases fibroblast activation protein (FAP) and dipeptidylpeptidase 4 (DPP-4)/CD26, we undertook the current study to determine the functional role of both enzymes in the invasion of RA synovial fibroblasts (RASFs) into articular cartilage.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CXCL12 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL12,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcl12 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/DPP4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Dipeptidyl Peptidase 4,
http://linkedlifedata.com/resource/pubmed/chemical/Dipeptidyl-Peptidase IV Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Dpp4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Gelatinases,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/fibroblast activation protein alpha
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1529-0131
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pubmed:author |
pubmed-author:BauerStefanS,
pubmed-author:BrentanoFabiaF,
pubmed-author:GayRenate ERE,
pubmed-author:GaySteffenS,
pubmed-author:HemmatazadHosseinH,
pubmed-author:HuberLars CLC,
pubmed-author:JüngelAstridA,
pubmed-author:KnuthAlexanderA,
pubmed-author:Maciejewska-RodriguezHannaH,
pubmed-author:MertensJoachim CJC,
pubmed-author:MichelBeat ABA,
pubmed-author:OspeltCarolineC,
pubmed-author:RennerChristophC,
pubmed-author:WüestThomasT
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1224-35
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20155839-Animals,
pubmed-meshheading:20155839-Arthritis, Rheumatoid,
pubmed-meshheading:20155839-Cartilage, Articular,
pubmed-meshheading:20155839-Cells, Cultured,
pubmed-meshheading:20155839-Chemokine CXCL12,
pubmed-meshheading:20155839-Dipeptidyl Peptidase 4,
pubmed-meshheading:20155839-Dipeptidyl-Peptidase IV Inhibitors,
pubmed-meshheading:20155839-Disease Models, Animal,
pubmed-meshheading:20155839-Enzyme Inhibitors,
pubmed-meshheading:20155839-Fibroblasts,
pubmed-meshheading:20155839-Gelatinases,
pubmed-meshheading:20155839-Humans,
pubmed-meshheading:20155839-Matrix Metalloproteinases,
pubmed-meshheading:20155839-Membrane Proteins,
pubmed-meshheading:20155839-Mice,
pubmed-meshheading:20155839-Mice, SCID,
pubmed-meshheading:20155839-Serine Endopeptidases,
pubmed-meshheading:20155839-Synovial Membrane
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pubmed:year |
2010
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pubmed:articleTitle |
Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.
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pubmed:affiliation |
University Hospital, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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