|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0035820,
umls-concept:C0039194,
umls-concept:C0039198,
umls-concept:C0042384,
umls-concept:C0521449,
umls-concept:C0544452,
umls-concept:C0851285,
umls-concept:C0871261,
umls-concept:C1156673,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2010-5-12
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|
pubmed:abstractText |
T lymphocytes have been implicated in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis (AAV). Patients with myeloperoxidase (MPO) antineutrophil cytoplasmic antibody (ANCA) experience relapses less frequently than those with proteinase 3 ANCA, suggesting greater immune regulation. This study was undertaken to investigate MPO-specific T cell reactivity during disease remission and the factors regulating their responsiveness.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
May
|
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pubmed:issn |
1529-0131
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
62
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1539-48
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pubmed:meshHeading |
pubmed-meshheading:20155828-Acute Disease,
pubmed-meshheading:20155828-Aged,
pubmed-meshheading:20155828-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:20155828-Biological Markers,
pubmed-meshheading:20155828-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20155828-Female,
pubmed-meshheading:20155828-Humans,
pubmed-meshheading:20155828-Immunosuppressive Agents,
pubmed-meshheading:20155828-Kynurenine,
pubmed-meshheading:20155828-Lymphocyte Count,
pubmed-meshheading:20155828-Male,
pubmed-meshheading:20155828-Middle Aged,
pubmed-meshheading:20155828-Neopterin,
pubmed-meshheading:20155828-Peroxidase,
pubmed-meshheading:20155828-Remission Induction,
pubmed-meshheading:20155828-T-Lymphocytes, Regulatory,
pubmed-meshheading:20155828-Tryptophan,
pubmed-meshheading:20155828-Vasculitis
|
|
pubmed:year |
2010
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|
pubmed:articleTitle |
Regulation of myeloperoxidase-specific T cell responses during disease remission in antineutrophil cytoplasmic antibody-associated vasculitis: the role of Treg cells and tryptophan degradation.
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pubmed:affiliation |
Imperial College London and Hammersmith Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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