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pubmed-article:20154604pubmed:abstractTextIndirect acute lung injury is associated with high morbidity and mortality. However, the underlying pathophysiology is only marginally understood, and so far no pathophysiologic-based remedy exists. We hypothesized that apoptosis of lung epithelial cells is a pathophysiological relevant process in the development of indirect acute lung injury and that it should be accessible to a siRNA-based therapeutic intervention in vivo.lld:pubmed
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pubmed-article:20154604pubmed:articleTitleTherapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury.lld:pubmed
pubmed-article:20154604pubmed:affiliationShock-Trauma Research Laboratories in the Division of Surgical Research and Department of Surgery, Rhode Island Hospital and Brown University, School of Medicine, Providence, RI, USA.lld:pubmed
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