Source:http://linkedlifedata.com/resource/pubmed/id/20154480
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
From results of ACTS-GC,postoperative adjuvant chemotherapy,administration of S-1 for one year has become the standard for gastric cancer of Stage II and III except T1. We inspected problems of adjuvant chemotherapy by S-1 by dose rate, an adverse event,and compliance. For the period from July 2006 to December 2008,among 41 cases of stage II/stage III gastric cancer, S-1 was as started as adjuvant therapy by for 28 cases (68.3%). Among 14 cases (63.6%) considered able to complete S-1 treatment for one year, 7 cases (31.8%) had to have their dose reduced or their administration schedule changed. No adverse event of grade 3/4 was found, but cancellation or reduced dose was necessary due to anorexia, malaise, diarrhea, severe skin reaction, and leukopenia resulting from myelosuppression. Thirteen patients took no S-1, and two (4.9%) of them took UFT, while 11 cases (26.8%) became a no-treatment follow-up group for reasons of age, coexisting symptoms and other reasons. The problem in the future is to improve compliance, and to establish a treatment strategy for patients who do not meet administration criteria and for patients for whom continuation of drug administration is impossible.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
255-8
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pubmed:meshHeading |
pubmed-meshheading:20154480-Adult,
pubmed-meshheading:20154480-Aged,
pubmed-meshheading:20154480-Aged, 80 and over,
pubmed-meshheading:20154480-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20154480-Chemotherapy, Adjuvant,
pubmed-meshheading:20154480-Drug Combinations,
pubmed-meshheading:20154480-Female,
pubmed-meshheading:20154480-Humans,
pubmed-meshheading:20154480-Male,
pubmed-meshheading:20154480-Middle Aged,
pubmed-meshheading:20154480-Neoplasm Staging,
pubmed-meshheading:20154480-Oxonic Acid,
pubmed-meshheading:20154480-Recurrence,
pubmed-meshheading:20154480-Stomach Neoplasms,
pubmed-meshheading:20154480-Tegafur
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pubmed:year |
2010
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pubmed:articleTitle |
[Problems of adjuvant chemotherapy with S-1 for gastric cancer].
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pubmed:affiliation |
Dept. of Surgery, National Hospital Organization Sendai Medical Center.
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pubmed:publicationType |
Journal Article,
English Abstract
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