Source:http://linkedlifedata.com/resource/pubmed/id/20153104
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2010-5-10
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| pubmed:abstractText |
We established a promising new experimental animal model with an orthotopic xenograft of esophageal cancer that successfully represents poor oral intake, a major clinical feature of esophageal cancer. The advantage of this model is that no surgical technique is required, only the injection of a cell suspension by a needle and syringe via the esophageal lumen from the mouth, which provides a high reproducibility of tumor implantation and a rapid progress of outcome. We propose that this model is useful to study cancer-related outcomes and for developing new therapies for esophageal cancer, and we expect it to make a contribution to clinical practice.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
|
| pubmed:issn |
1872-7980
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| pubmed:author |
pubmed-author:MatsuokaJunjiJ,
pubmed-author:NagaishiKaoriK,
pubmed-author:NagasakaTakeshiT,
pubmed-author:NaomotoYoshioY,
pubmed-author:OharaToshiakiT,
pubmed-author:SakuramaKazufumiK,
pubmed-author:ShirakawaYasuhiroY,
pubmed-author:TakaokaMunenoriM,
pubmed-author:TakedaHaruoH,
pubmed-author:TanakaNoriakiN,
pubmed-author:YamatsujiTomokiT
|
| pubmed:copyrightInfo |
Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:day |
28
|
| pubmed:volume |
293
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
207-12
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| pubmed:meshHeading |
pubmed-meshheading:20153104-Animals,
pubmed-meshheading:20153104-Cell Line, Tumor,
pubmed-meshheading:20153104-Disease Models, Animal,
pubmed-meshheading:20153104-Eating,
pubmed-meshheading:20153104-Esophageal Neoplasms,
pubmed-meshheading:20153104-Esophageal Stenosis,
pubmed-meshheading:20153104-Male,
pubmed-meshheading:20153104-Mice,
pubmed-meshheading:20153104-Mice, Inbred BALB C,
pubmed-meshheading:20153104-Mice, Nude,
pubmed-meshheading:20153104-Neoplasm Transplantation,
pubmed-meshheading:20153104-Transplantation, Heterologous
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
The establishment of a new mouse model with orthotopic esophageal cancer showing the esophageal stricture.
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| pubmed:affiliation |
Department of Gastroenterological Surgery, Transplant, and Surgical Oncology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
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| pubmed:publicationType |
Journal Article
|