Linked Life Data

20152397

Source:http://linkedlifedata.com/resource/pubmed/id/20152397

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-2-15
pubmed:abstractText
This paper describes the simultaneous determination of ascorbic acid (AA), dopamine (DA), uric acid (UA) and xanthine (XN) using an ultrathin electropolymerized film of 2-amino-1,3,4-thiadiazole (p-ATD) modified glassy carbon (GC) electrode in 0.20 M phosphate buffer solution (pH 5.0). Bare GC electrode failed to resolve the voltammetric signals of AA, DA, UA and XN in a mixture. On the other hand, the p-ATD modified electrode separated the voltammetric signals of AA, DA, UA and XN with potential differences of 110, 152 and 392 mV between AA-DA, DA-UA and UA-XN, respectively and also enhanced their oxidation peak currents. The modified electrode could sense 5 microM DA and 10 microM each UA and XN even in the presence of 200 microM AA. The oxidation currents were increased from 30 to 300 microM for AA, 5 to 50 microM for DA and 10 to 100 microM for each UA and XN, and the lowest detection limit was found to be 2.01, 0.33, 0.19 and 0.59 microM for AA, DA, UA and XN, respectively (S/N=3). The practical application of the present modified electrode was demonstrated by the determination of AA, UA and XN in human urine samples.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1873-3573
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1686-91
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Simultaneous determination of ascorbic acid, dopamine, uric acid and xanthine using a nanostructured polymer film modified electrode.
pubmed:affiliation
Department of Chemistry, Gandhigram Rural University, Gandhigram 624 302, Dindigul, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Validation Studies