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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
Mammalian neurulation is completed when the dorsolateral neural folds bend inwards, their tips make adhesive contacts across the midline, and the epithelia remodel to create a closed neural tube. Two recent papers (one by Camerer et al. in this issue of Developmental Cell) demonstrate a vital role for protease-activated G protein-coupled receptor signaling in these late closure events, opening up new avenues for exploring the molecular basis of mammalian neural tube morphogenesis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1878-1551
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-2
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pubmed:meshHeading |
pubmed-meshheading:20152170-Animals,
pubmed-meshheading:20152170-Central Nervous System,
pubmed-meshheading:20152170-Epithelial Cells,
pubmed-meshheading:20152170-Humans,
pubmed-meshheading:20152170-Mice,
pubmed-meshheading:20152170-Neural Tube,
pubmed-meshheading:20152170-Neural Tube Defects,
pubmed-meshheading:20152170-Neurons,
pubmed-meshheading:20152170-Receptor, PAR-1,
pubmed-meshheading:20152170-Receptor, PAR-2,
pubmed-meshheading:20152170-Receptors, G-Protein-Coupled,
pubmed-meshheading:20152170-Receptors, Proteinase-Activated,
pubmed-meshheading:20152170-Signal Transduction,
pubmed-meshheading:20152170-Stem Cells
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pubmed:year |
2010
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pubmed:articleTitle |
Defining a PARticular pathway of neural tube closure.
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pubmed:affiliation |
UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK. a.copp@ich.ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Comment
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