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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
2010-8-13
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pubmed:abstractText |
CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mIns concentration, pointing to gliosis and astrocytic proliferation.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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|
pubmed:issn |
1936-959X
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1347-9
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pubmed:meshHeading |
pubmed-meshheading:20150306-Adult,
pubmed-meshheading:20150306-Aspartic Acid,
pubmed-meshheading:20150306-Cerebellum,
pubmed-meshheading:20150306-Choline,
pubmed-meshheading:20150306-Humans,
pubmed-meshheading:20150306-Inositol,
pubmed-meshheading:20150306-Lactic Acid,
pubmed-meshheading:20150306-Magnetic Resonance Spectroscopy,
pubmed-meshheading:20150306-Male,
pubmed-meshheading:20150306-Middle Aged,
pubmed-meshheading:20150306-Xanthomatosis, Cerebrotendinous,
pubmed-meshheading:20150306-Young Adult
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
MR spectroscopy detects lipid peaks in cerebrotendinous xanthomatosis.
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pubmed:affiliation |
Department of Neurology, Clinics Hospital of the University of Sao Paulo, School of Medicine, Sao Paulo, Brazil.
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pubmed:publicationType |
Journal Article,
Case Reports
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