rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11-12
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pubmed:dateCreated |
2010-3-8
|
pubmed:abstractText |
A noncoding RNA, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), is upregulated in several malignant tumors. Its expression in neuroblastoma, however, is not known, and the regulatory mechanisms of MALAT1 gene expression have not been elucidated. The aim of this study is to clarify how MALAT1 gene expression is altered by extracellular signals in the SK-N-SH neuroblastoma cell line and to define its proximal promoter in order to study the mechanism of MALAT1 gene expression.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1879-0631
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
13
|
pubmed:volume |
86
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
455-60
|
pubmed:dateRevised |
2010-5-17
|
pubmed:meshHeading |
pubmed-meshheading:20149803-Brain Neoplasms,
pubmed-meshheading:20149803-Calcium,
pubmed-meshheading:20149803-Cell Line, Tumor,
pubmed-meshheading:20149803-Cyclic AMP Response Element-Binding Protein,
pubmed-meshheading:20149803-Humans,
pubmed-meshheading:20149803-Informatics,
pubmed-meshheading:20149803-Neuroblastoma,
pubmed-meshheading:20149803-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20149803-Oxytocin,
pubmed-meshheading:20149803-RNA, Neoplasm,
pubmed-meshheading:20149803-Receptors, Oxytocin,
pubmed-meshheading:20149803-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20149803-Tumor Markers, Biological
|
pubmed:year |
2010
|
pubmed:articleTitle |
Oxytocin stimulates expression of a noncoding RNA tumor marker in a human neuroblastoma cell line.
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pubmed:affiliation |
Department of Pharmacology, Division of Molecular Pharmacology, Jichi Medical University, Tochigi 329-0498, Japan. t_koshi@jichi.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|