Source:http://linkedlifedata.com/resource/pubmed/id/20149499
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-3-22
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pubmed:abstractText |
A rapid preparation of compounds (1-24), with the objective of discovering novel and potent anti-inflammatory agent. All the compounds exhibited anti-inflammatory and analgesic activities at the dose 50 mg/kg p.o. The compound 1-(2',4'-Chloroacridine-9'-yl)-3-(5'-pyridine-4-yl)-(1,3,4-oxadiazol-2-yl-thiomethyl)-pyrazole-5-one 24 showed better anti-inflammatory and analgesic activities at the three graded dose of 25, 50 and 100 mg/kg p.o.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1768-3254
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1772-6
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pubmed:meshHeading |
pubmed-meshheading:20149499-Analgesics,
pubmed-meshheading:20149499-Animals,
pubmed-meshheading:20149499-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:20149499-Drug Evaluation, Preclinical,
pubmed-meshheading:20149499-Molecular Structure,
pubmed-meshheading:20149499-Pyrazoles,
pubmed-meshheading:20149499-Rats,
pubmed-meshheading:20149499-Stereoisomerism
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pubmed:year |
2010
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pubmed:articleTitle |
Synthesis of substituted acridinyl pyrazoline derivatives and their evaluation for anti-inflammatory activity.
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pubmed:affiliation |
Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut (U.P.)-250004, India.
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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