Linked Life Data

20146696

Source:http://linkedlifedata.com/resource/pubmed/id/20146696

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-2-11
pubmed:abstractText
Due to limitations posed by the restrictive blood-brain barrier, conventional drug delivery systems do not provide adequate cyto-architecture restoration and connection patterns that are essential for functional recovery in neurodegenerative disorders (NDs). Nanotechnology employs engineered materials or devices that interact with biological systems at a molecular level and could revolutionize the treatment of NDs by stimulating, responding to, and interacting with target sites to induce physiological responses while minimizing side effects. This review provides a concise discussion of the current applications of nano-enabled drug-delivery systems for the treatment of NDs, in particular Alzheimer's and Parkinson's diseases, and explores the future applications of nanotechnology in clinical neuroscience to develop innovative therapeutic modalities for the treatment of NDs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1749-6632
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1184
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
154-72
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Advances in the treatment of neurodegenerative disorders employing nanotechnology.
pubmed:affiliation
Department of Neurology, Division of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa. gmodicns@mweb.co.za
pubmed:publicationType
Journal Article, Review