20145583

Source:http://linkedlifedata.com/resource/pubmed/id/20145583

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001645, umls-concept:C0011847, umls-concept:C0030705, umls-concept:C0948089, umls-concept:C1421314, umls-concept:C1704675, umls-concept:C1882417
pubmed:issue	4
pubmed:dateCreated	2010-3-19
pubmed:abstractText	UCP2 -866G>A (rs659366) has been implicated in cardiometabolic disease and represents a novel candidate gene for beta-blocker response, particularly among patients with diabetes. We assessed the function of -866G>A and its role as a modifier of beta-blocker treatment outcomes by diabetes status in an acute coronary syndrome (ACS) cohort.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/K23 HL 091120, http://linkedlifedata.com/resource/pubmed/grant/K23 HL091120-03, http://linkedlifedata.com/resource/pubmed/grant/K23 HL091120-04, http://linkedlifedata.com/resource/pubmed/grant/P30 DK056341-08, http://linkedlifedata.com/resource/pubmed/grant/P30 DK056341-09, http://linkedlifedata.com/resource/pubmed/grant/P30 DK56341, http://linkedlifedata.com/resource/pubmed/grant/P50 HL 077113, http://linkedlifedata.com/resource/pubmed/grant/P50 HL077113-04, http://linkedlifedata.com/resource/pubmed/grant/P50 HL077113-05
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101231005
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Ion Channels, http://linkedlifedata.com/resource/pubmed/chemical/Mitochondrial Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/mitochondrial uncoupling protein 2
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1744-6880
pubmed:author	pubmed-author:BeitelsheesAmber LAL, pubmed-author:CresciSharonS, pubmed-author:FabbriniElisaE, pubmed-author:FinckBrian NBN, pubmed-author:KellyDaniel PDP, pubmed-author:KirkErikE, pubmed-author:KleinSamuelS, pubmed-author:LeoneTeresa CTC, pubmed-author:ProvinceMichael AMA, pubmed-author:SpertusJohn AJA, pubmed-author:WuJunJ, pubmed-author:ZinehIssamI
pubmed:issnType	Electronic
pubmed:volume	20
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	231-8
pubmed:dateRevised	2011-7-27
pubmed:meshHeading	pubmed-meshheading:20145583-Acute Coronary Syndrome, pubmed-meshheading:20145583-Adrenergic beta-Antagonists, pubmed-meshheading:20145583-Aged, pubmed-meshheading:20145583-Cell Line, pubmed-meshheading:20145583-Cohort Studies, pubmed-meshheading:20145583-Diabetes Complications, pubmed-meshheading:20145583-Diabetes Mellitus, pubmed-meshheading:20145583-Female, pubmed-meshheading:20145583-Gene Expression, pubmed-meshheading:20145583-Genetic Association Studies, pubmed-meshheading:20145583-Humans, pubmed-meshheading:20145583-Ion Channels, pubmed-meshheading:20145583-Male, pubmed-meshheading:20145583-Middle Aged, pubmed-meshheading:20145583-Mitochondrial Proteins, pubmed-meshheading:20145583-Obesity, pubmed-meshheading:20145583-Pharmacogenetics, pubmed-meshheading:20145583-Polymorphism, Single Nucleotide, pubmed-meshheading:20145583-Recombinant Proteins, pubmed-meshheading:20145583-Transcription, Genetic, pubmed-meshheading:20145583-Transfection
pubmed:year	2010
pubmed:articleTitle	Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.
pubmed:affiliation	Endocrinology, Diabetes and Nutrition Division, University of Maryland School of Medicine, 660 W. Redwood Street, Baltimore, MD 21201, USA. abeitels@medicine.umaryland.edu
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural