Source:http://linkedlifedata.com/resource/pubmed/id/20144871
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-2-22
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pubmed:abstractText |
A series of 2-substituted 1,2-dihydro-3-phenyl-1-(trichloromethyl)benzo[b][1,6]naphthyridines were synthesized and their in vitro antiproliferative activities were examined against human solid tumor cell lines and relevant strains of bacteria and Candida. The compounds induced considerably growth inhibition in all cancer cell lines, whilst showed inactive against microbial strains. Furthermore, we found analog 2-ethoxy-1H-pyrano[4,3-b]quinoline as selective inhibitor of microbial strains.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1464-3405
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1504-6
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pubmed:meshHeading |
pubmed-meshheading:20144871-Anti-Bacterial Agents,
pubmed-meshheading:20144871-Antifungal Agents,
pubmed-meshheading:20144871-Antineoplastic Agents,
pubmed-meshheading:20144871-Cell Line, Tumor,
pubmed-meshheading:20144871-Drug Screening Assays, Antitumor,
pubmed-meshheading:20144871-Humans,
pubmed-meshheading:20144871-Naphthyridines
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pubmed:year |
2010
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pubmed:articleTitle |
Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines.
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pubmed:affiliation |
Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius LT-03225, Lithuania.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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