Source:http://linkedlifedata.com/resource/pubmed/id/20140445
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
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| pubmed:dateCreated |
2010-6-28
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| pubmed:abstractText |
The frequency, clinical presentation, radiological features, and prognosis of remote cerebral hematomas (rPH) are not well known. We report our experience in patients treated with intravenous rt-PA. We reviewed our database of consecutive patients treated at our hospital from 1999 to 2008. We used the inclusion/exclusion criteria of the ECASS-2 study from 1999 to 2003, and the criteria of the SITS-MOST study since 2004. A follow-up CT scan was obtained in all of the patients within the first 36 h of treatment. Cerebral hemorrhagic complications were classified as hemorrhagic infarction (HI-1/HI-2) and parenchymal hematoma (PH-1/PH-2). The rPH was defined as any extra-ischemic hemorrhagic lesion observed in the follow-up CT. A favorable outcome was defined as a score 0-1 on the Rankin scale at 3 months. We treated 210 patients (mean age 67.6 +/- 12.4 years, 56% were men). The median initial NIHSS score was 14. Patients with rPH (n = 7) had a mean age of 72.4 +/- 7.5 years and 43% were men. The median initial NIHSS score was 15. Three patients had multifocal rPH; three patients had a single rPH and in one patient the rPH was associated with a PH-2. rPH were lobar in six patients and in brainstem in one patient, symptomatic in five patients and asymptomatic in two patients. The outcome was unfavorable in all of them; four deaths (57%) were recorded. Remote cerebral hemorrhage is an infrequent complication after rt-PA treatment (3.3%), it is usually lobar and symptomatic and has an uniformly unfavorable outcome.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
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| pubmed:issn |
1432-1459
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| pubmed:author |
pubmed-author:AlcoleaDanielD,
pubmed-author:De JuanManuelM,
pubmed-author:Delgado-MederosRaquelR,
pubmed-author:MarínRebecaR,
pubmed-author:MarquiéMartaM,
pubmed-author:Martí-FàbregasJoanJ,
pubmed-author:Martí-VilaltaJosep LluisJL,
pubmed-author:Martínez-HernándezEugeniaE,
pubmed-author:Martínez-RamírezSergiS
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| pubmed:issnType |
Electronic
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| pubmed:volume |
257
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1062-6
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| pubmed:meshHeading |
pubmed-meshheading:20140445-Aged,
pubmed-meshheading:20140445-Aged, 80 and over,
pubmed-meshheading:20140445-Brain,
pubmed-meshheading:20140445-Cerebral Arteries,
pubmed-meshheading:20140445-Cerebral Hemorrhage,
pubmed-meshheading:20140445-Female,
pubmed-meshheading:20140445-Fibrinolytic Agents,
pubmed-meshheading:20140445-Humans,
pubmed-meshheading:20140445-Hypoxia-Ischemia, Brain,
pubmed-meshheading:20140445-Iatrogenic Disease,
pubmed-meshheading:20140445-Infusions, Intravenous,
pubmed-meshheading:20140445-Intracranial Thrombosis,
pubmed-meshheading:20140445-Male,
pubmed-meshheading:20140445-Middle Aged,
pubmed-meshheading:20140445-Mortality,
pubmed-meshheading:20140445-Recombinant Proteins,
pubmed-meshheading:20140445-Retrospective Studies,
pubmed-meshheading:20140445-Stroke,
pubmed-meshheading:20140445-Thrombolytic Therapy,
pubmed-meshheading:20140445-Tissue Plasminogen Activator
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| pubmed:year |
2010
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| pubmed:articleTitle |
Remote cerebral hematomas in patients treated with intravenous rt-PA.
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| pubmed:affiliation |
Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain. emartinezh@santpau.cat
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| pubmed:publicationType |
Journal Article
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