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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-4-12
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pubmed:abstractText |
The C-allele of rs13266634 located in SLC30A8 (ZNT8) has been strongly associated with decreased insulin release and with type 2 diabetes (T2D) susceptibility in some but not all studies. To shed further light on this issue, we performed a meta-analysis of the association between rs13266634 and T2D in different ethnic groups and assessed the relationships between SLC30A8 genotypes and some properties of isolated human islets.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1096-7206
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2010. Published by Elsevier Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-82
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20138556-Arginine,
pubmed-meshheading:20138556-Asian Continental Ancestry Group,
pubmed-meshheading:20138556-Cation Transport Proteins,
pubmed-meshheading:20138556-Diabetes Mellitus, Type 2,
pubmed-meshheading:20138556-European Continental Ancestry Group,
pubmed-meshheading:20138556-Genotype,
pubmed-meshheading:20138556-Glucagon,
pubmed-meshheading:20138556-Glucose,
pubmed-meshheading:20138556-Glyburide,
pubmed-meshheading:20138556-Humans,
pubmed-meshheading:20138556-Insulin,
pubmed-meshheading:20138556-Islets of Langerhans,
pubmed-meshheading:20138556-Polymorphism, Genetic,
pubmed-meshheading:20138556-Risk
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pubmed:year |
2010
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pubmed:articleTitle |
Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.
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pubmed:affiliation |
CNRS UMR 8090, Institute of Biology, Genomics and Molecular Physiology of Metabolic Diseases, Lille, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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