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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-3-2
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pubmed:abstractText |
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are common primary hepatic malignancies. Their immunohistological differentiation using specific markers is pivotal for treatment and prognosis. We found alphavbeta6 integrin strongly upregulated in biliary fibrosis, but its expression in primary and secondary liver tumours is unknown. Here, we aimed to evaluate the diagnostic applicability of alphavbeta6 integrin in differentiating primary liver cancers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
362-9
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pubmed:meshHeading |
pubmed-meshheading:20137822-Aged,
pubmed-meshheading:20137822-Aged, 80 and over,
pubmed-meshheading:20137822-Antigens, Neoplasm,
pubmed-meshheading:20137822-Bile Duct Neoplasms,
pubmed-meshheading:20137822-Bile Ducts, Intrahepatic,
pubmed-meshheading:20137822-Carcinoma, Hepatocellular,
pubmed-meshheading:20137822-Cell Line, Tumor,
pubmed-meshheading:20137822-Cholangiocarcinoma,
pubmed-meshheading:20137822-Cholangitis, Sclerosing,
pubmed-meshheading:20137822-Diagnosis, Differential,
pubmed-meshheading:20137822-Female,
pubmed-meshheading:20137822-Humans,
pubmed-meshheading:20137822-Integrins,
pubmed-meshheading:20137822-Keratin-20,
pubmed-meshheading:20137822-Keratin-7,
pubmed-meshheading:20137822-Liver Neoplasms,
pubmed-meshheading:20137822-Male,
pubmed-meshheading:20137822-Middle Aged,
pubmed-meshheading:20137822-Sensitivity and Specificity,
pubmed-meshheading:20137822-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma.
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pubmed:affiliation |
Institute of Clinical Pharmacology and Visceral Research, University of Bern, Murtenstrasse 35, Bern, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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