Source:http://linkedlifedata.com/resource/pubmed/id/20135076
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-3-2
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pubmed:abstractText |
Antithrombotic therapy for the acute management of thrombotic disorders has been stimulated and guided actively by our current understanding of platelet biology, coagulation proteases, and vascular science. A translatable platform for coagulation, based soundly on biochemistry, enzymology and cellular events on platelets and tissue factor-baring cells, introduces fundamental constructs, mechanistic clarity, and an unparalleled opportunity for accelerating the development and clinical investigation of both disease- and patient-specific therapies. In the current review, we build upon and expand substantially our observations surrounding nucleic acids as antithrombotic agents.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0340-6245
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
586-95
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pubmed:dateRevised |
2010-10-7
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics.
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pubmed:affiliation |
Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina 27715, USA. Becke021@mc.duke.edu
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pubmed:publicationType |
Journal Article,
Review
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