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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-6-17
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pubmed:abstractText |
In the absence of pathology, cannabinoid-induced depression of gastrointestinal (GI) motility is thought to be mediated primarily by CB1 receptors, whereas the role of CB2 receptors is still unclear. The aim of this work was to radiographically analyze the acute effect of the mixed cannabinoid agonist WIN 55,212-2 (WIN) on GI motor function in the rat, focusing on the involvement of CB1 and CB2 receptors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Benzoxazines,
http://linkedlifedata.com/resource/pubmed/chemical/Bornanes,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles,
http://linkedlifedata.com/resource/pubmed/chemical/Morpholines,
http://linkedlifedata.com/resource/pubmed/chemical/Naphthalenes,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Cannabinoid, CB1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Cannabinoid, CB2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cannabinoid,
http://linkedlifedata.com/resource/pubmed/chemical/SR 144528,
http://linkedlifedata.com/resource/pubmed/chemical/Win 55212-2,
http://linkedlifedata.com/resource/pubmed/chemical/iodopravadoline
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1365-2982
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
694-e206
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pubmed:meshHeading |
pubmed-meshheading:20132133-Animals,
pubmed-meshheading:20132133-Benzoxazines,
pubmed-meshheading:20132133-Bornanes,
pubmed-meshheading:20132133-Dose-Response Relationship, Drug,
pubmed-meshheading:20132133-Drug Synergism,
pubmed-meshheading:20132133-Gastric Emptying,
pubmed-meshheading:20132133-Gastrointestinal Motility,
pubmed-meshheading:20132133-Gastrointestinal Tract,
pubmed-meshheading:20132133-Indoles,
pubmed-meshheading:20132133-Male,
pubmed-meshheading:20132133-Morpholines,
pubmed-meshheading:20132133-Naphthalenes,
pubmed-meshheading:20132133-Pyrazoles,
pubmed-meshheading:20132133-Rats,
pubmed-meshheading:20132133-Rats, Wistar,
pubmed-meshheading:20132133-Receptor, Cannabinoid, CB1,
pubmed-meshheading:20132133-Receptor, Cannabinoid, CB2,
pubmed-meshheading:20132133-Receptors, Cannabinoid
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pubmed:year |
2010
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pubmed:articleTitle |
The cannabinoid antagonist SR144528 enhances the acute effect of WIN 55,212-2 on gastrointestinal motility in the rat.
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pubmed:affiliation |
Departamento de Farmacología y Nutrición, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, 28922 Alcorcón, Madrid, Spain. raquel.abalo@urjc.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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