Source:http://linkedlifedata.com/resource/pubmed/id/20132020
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0008115,
umls-concept:C0016452,
umls-concept:C0017337,
umls-concept:C0031921,
umls-concept:C0042637,
umls-concept:C0080194,
umls-concept:C0081786,
umls-concept:C0205210,
umls-concept:C0332307,
umls-concept:C0679058,
umls-concept:C1257893,
umls-concept:C1547699,
umls-concept:C1704711,
umls-concept:C2700640
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| pubmed:issue |
6
|
| pubmed:dateCreated |
2010-6-3
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| pubmed:abstractText |
Vibrio parahaemolyticus is a major cause of foodborne gastroenteritis in China, Japan, and other countries. The pandemic O3:K6 clone, which harbors thermostable direct hemolysin [tdh] gene and toxRS/new gene, is mainly responsible for the foodborne outbreaks after 1995. Previous studies showed that genes in the pathogenicity island-1 (VPaI-1) and VPaI-5 are harbored only by pandemic strains, whereas genes in VPaI-7 and type III secretion system 2 are closely associated with tdh-positive strains of V. parahaemolyticus. In this study, we examined the distribution of genes encoding VPaI-2, VPaI-3, VPaI-4, VPaI-6, type VI secretion systems (T6SS), biofilm, and type I pilus in 71 food and 116 clinical strains of V. parahaemolyticus. The results showed that most of the pandemic strains of V. parahaemolyticus harbored the complete genes of VPaI-2, T6SS, and type I pilus. In contrast, most of the pathogenic strains (harboring tdh gene or TDH-related hemolysin [trh] gene) and nonpathogenic strains (harboring neither tdh gene nor trh gene) contained partial genes of VPaI-2, T6SS, and type I pilus. Genes of VPaI-4 were exclusively present in the pandemic strains. Genes of VPaI-3 were present in most of the pandemic strains and a small percentage of nonpathogenic strains, mainly O3:K6 strains. VPaI-6 and biofilm-associated genes were harbored by almost all the strains, irrespective of their pandemic, pathogenic, or nonpathogenic traits.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1556-7125
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| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
649-58
|
| pubmed:meshHeading |
pubmed-meshheading:20132020-Bacterial Toxins,
pubmed-meshheading:20132020-Biofilms,
pubmed-meshheading:20132020-China,
pubmed-meshheading:20132020-Disease Outbreaks,
pubmed-meshheading:20132020-Fimbriae, Bacterial,
pubmed-meshheading:20132020-Food Microbiology,
pubmed-meshheading:20132020-Foodborne Diseases,
pubmed-meshheading:20132020-Genes, Bacterial,
pubmed-meshheading:20132020-Genomic Islands,
pubmed-meshheading:20132020-Hemolysin Proteins,
pubmed-meshheading:20132020-Humans,
pubmed-meshheading:20132020-Polymerase Chain Reaction,
pubmed-meshheading:20132020-Seafood,
pubmed-meshheading:20132020-Secretory Pathway,
pubmed-meshheading:20132020-Species Specificity,
pubmed-meshheading:20132020-Vibrio Infections,
pubmed-meshheading:20132020-Vibrio parahaemolyticus,
pubmed-meshheading:20132020-Virulence,
pubmed-meshheading:20132020-Virulence Factors
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
Distribution of genes encoding four pathogenicity islands (VPaIs), T6SS, biofilm, and type I pilus in food and clinical strains of Vibrio parahaemolyticus in China.
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| pubmed:affiliation |
Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|