Linked Life Data

20127584

Source:http://linkedlifedata.com/resource/pubmed/id/20127584

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-2-3
pubmed:abstractText
Clinically apparent and frequently debilitating neurologic disease is common with infection by HIV type 1. Approximately one half of all HIV-infected patients will develop clinically significant neurologic disease, and the frequency with which neuropathologic abnormalities are detected at autopsy in some series exceeds 90%, suggesting that neurologic findings are often overlooked. Not surprisingly, careful neurologic examination, even in the absence of specific complaints by the HIV-infected patient, often reveals evidence of central or peripheral nervous system dysfunction. Although neurologic disease typically occurs with advanced disease and profound immunosuppression, it may also occur during early stages of the infection. In as many as 20% of individuals, neurologic disease is the harbinger of AIDS. The spectrum of neurologic disorders that complicate HIV infection is extremely broad; any part of the neuraxis may be affected. Additionally, the complexity of evaluating the HIV-infected person with neurologic disease is increased by the relatively high frequency with which more than one disease concurrently affects the nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1098-9021
pubmed:author
pubmed:copyrightInfo
(c) Thieme Medical Publishers.
pubmed:issnType
Electronic
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
66-70
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Pearls: neurologic complications of HIV/AIDS.
pubmed:affiliation
Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA. jrbneuro@uky.edu
pubmed:publicationType
Journal Article