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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-3
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pubmed:abstractText |
Tetherin/BST-2 is a recently-identified potent restriction factor in human cells that restricts HIV particle release following particle formation and budding at the plasma membrane. Vpu counteracts tetherin's restriction of particle release in a manner that has not yet been fully defined. We recently identified calcium-modulating cyclophilin ligand (CAML) as a Vpu-interacting protein that also restricts particle release. We hypothesized that CAML may act to enhance tetherin-mediated restriction of particle release and thereby explain how two distinct factors could be responsible for Vpu-responsive restriction.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-10329429,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-12919676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-12956872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-1433512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-14657387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-16699598,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-18424167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-18500349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-19036818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-19091864,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-19214216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-19244337,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-7853484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-8139011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-8551619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-8621480,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20126395-9660940
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/BST2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CAMLG protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/GPI-Linked Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Human Immunodeficiency Virus...,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Regulatory and Accessory...,
http://linkedlifedata.com/resource/pubmed/chemical/vpu protein, Human...
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e9005
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20126395-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:20126395-Animals,
pubmed-meshheading:20126395-Antigens, CD,
pubmed-meshheading:20126395-Blotting, Western,
pubmed-meshheading:20126395-COS Cells,
pubmed-meshheading:20126395-Cell Line,
pubmed-meshheading:20126395-Cell Line, Tumor,
pubmed-meshheading:20126395-Cercopithecus aethiops,
pubmed-meshheading:20126395-GPI-Linked Proteins,
pubmed-meshheading:20126395-HIV-1,
pubmed-meshheading:20126395-HeLa Cells,
pubmed-meshheading:20126395-Human Immunodeficiency Virus Proteins,
pubmed-meshheading:20126395-Humans,
pubmed-meshheading:20126395-Jurkat Cells,
pubmed-meshheading:20126395-Membrane Glycoproteins,
pubmed-meshheading:20126395-RNA Interference,
pubmed-meshheading:20126395-Transfection,
pubmed-meshheading:20126395-Viral Regulatory and Accessory Proteins,
pubmed-meshheading:20126395-Virion,
pubmed-meshheading:20126395-Virus Replication
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pubmed:year |
2010
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pubmed:articleTitle |
CAML does not modulate tetherin-mediated restriction of HIV-1 particle release.
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pubmed:affiliation |
Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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