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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0013216,
umls-concept:C0021756,
umls-concept:C0030705,
umls-concept:C0079189,
umls-concept:C0079460,
umls-concept:C0205210,
umls-concept:C0278883,
umls-concept:C1274040,
umls-concept:C1883562,
umls-concept:C2004454,
umls-concept:C2603343
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pubmed:issue |
7
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pubmed:dateCreated |
2010-2-25
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pubmed:abstractText |
Recovery of lymphocyte populations after lymphocyte depletion is implicated in therapeutic immune pathways in animal models and in patients with cancer. We sought to evaluate the effects of chemotherapy-induced lymphodepletion followed by granulocyte-macrophage colony-stimulating factor (GM-CSF) and high-dose interleukin-2 (IL-2) therapy on clinical response and the recovery of lymphocyte subcompartments in patients with metastatic melanoma.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-10561265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-10925249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-10925359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-10952725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-11875462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-12122106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-12124318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-12682289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-12826605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-14647496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-15004146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-15613700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-15728465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-15826823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-15870015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-16204013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-17237035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-18483384,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20124177-308987
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:AhonenCoryC,
pubmed-author:AtkinsMichael BMB,
pubmed-author:ClarkJoseph IJI,
pubmed-author:CrocenziTodd STS,
pubmed-author:CrosbyNancy ANA,
pubmed-author:ErnstoffMarc SMS,
pubmed-author:FisherJan LJL,
pubmed-author:FuseShinichiroS,
pubmed-author:GunturuKrishna SKS,
pubmed-author:MackenzieTodd ATA,
pubmed-author:MargolinKim AKA,
pubmed-author:McDermottDavidD,
pubmed-author:MeehanKenneth RKR,
pubmed-author:NoelleRandolph JRJ,
pubmed-author:TurkMary JoMJ,
pubmed-author:UsherwoodEdward JEJ
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
28
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1196-202
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pubmed:dateRevised |
2011-7-25
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pubmed:meshHeading |
pubmed-meshheading:20124177-Adult,
pubmed-meshheading:20124177-Aged,
pubmed-meshheading:20124177-CD4 Lymphocyte Count,
pubmed-meshheading:20124177-CD8-Positive T-Lymphocytes,
pubmed-meshheading:20124177-Female,
pubmed-meshheading:20124177-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:20124177-Humans,
pubmed-meshheading:20124177-Interleukin-2,
pubmed-meshheading:20124177-Lymphocyte Depletion,
pubmed-meshheading:20124177-Male,
pubmed-meshheading:20124177-Melanoma,
pubmed-meshheading:20124177-Middle Aged,
pubmed-meshheading:20124177-T-Lymphocytes, Regulatory
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pubmed:year |
2010
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pubmed:articleTitle |
Cytokine working group study of lymphodepleting chemotherapy, interleukin-2, and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma: clinical outcomes and peripheral-blood cell recovery.
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pubmed:affiliation |
Section of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH 03756, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial, Phase II
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