|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0039286,
umls-concept:C0057223,
umls-concept:C0087111,
umls-concept:C0205210,
umls-concept:C0750502,
umls-concept:C1274040,
umls-concept:C1280500,
umls-concept:C1332830,
umls-concept:C1412077,
umls-concept:C1516213,
umls-concept:C1522673,
umls-concept:C1882417
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2010-3-9
|
|
pubmed:abstractText |
The clinical efficacy of tamoxifen is suspected to be influenced by the activity of drug-metabolizing enzymes and transporters involved in the formation, metabolism, and elimination of its active forms. We investigated relationships of polymorphisms in transporter genes and CYP2D6 to clinical outcome of patients receiving tamoxifen.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1527-7755
|
|
pubmed:author |
pubmed-author:AkiFuminoriF,
pubmed-author:DestaZeruesenayZ,
pubmed-author:FlockhartDavid ADA,
pubmed-author:HirataKoichiK,
pubmed-author:HosonoNaoyaN,
pubmed-author:ImamuraChiyo KCK,
pubmed-author:KiyotaniKazumaK,
pubmed-author:KuboMichiakiM,
pubmed-author:MushirodaTaiseiT,
pubmed-author:NakamuraYusukeY,
pubmed-author:OhsumiShozoS,
pubmed-author:OkazakiMinoruM,
pubmed-author:SasaMitsunoriM,
pubmed-author:SkaarTodd CTC,
pubmed-author:TakatsukaYuichiY,
pubmed-author:TanigawaraYusukeY,
pubmed-author:TsunodaTatsuhikoT,
pubmed-author:YamakawaTakashiT,
pubmed-author:ZembutsuHitoshiH
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
10
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1287-93
|
|
pubmed:dateRevised |
2010-9-7
|
|
pubmed:meshHeading |
pubmed-meshheading:20124171-ATP-Binding Cassette Transporters,
pubmed-meshheading:20124171-Adult,
pubmed-meshheading:20124171-Aged,
pubmed-meshheading:20124171-Aged, 80 and over,
pubmed-meshheading:20124171-Antineoplastic Agents, Hormonal,
pubmed-meshheading:20124171-Breast Neoplasms,
pubmed-meshheading:20124171-Chemotherapy, Adjuvant,
pubmed-meshheading:20124171-Cytochrome P-450 CYP2D6,
pubmed-meshheading:20124171-Drug Resistance, Neoplasm,
pubmed-meshheading:20124171-Female,
pubmed-meshheading:20124171-Humans,
pubmed-meshheading:20124171-Japan,
pubmed-meshheading:20124171-Middle Aged,
pubmed-meshheading:20124171-Polymorphism, Single Nucleotide,
pubmed-meshheading:20124171-Prognosis,
pubmed-meshheading:20124171-Survival Analysis,
pubmed-meshheading:20124171-Tamoxifen
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
|
|
pubmed:affiliation |
Laboratories for Pharmacogenetics, Genotyping Development, and Medical Informatics, RIKEN Center for Genomic Medicine, Yokohama, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
