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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-4-6
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pubmed:abstractText |
A consistent body of evidence supports a role of reduced neurotrophic signaling in the pathophysiology of major depressive disorder (MDD) and suicidal behavior. Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1538-3636
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pubmed:author |
pubmed-author:BinderElisabeth BEB,
pubmed-author:BradleyBekh BBB,
pubmed-author:HenningsJohannesJ,
pubmed-author:HolsboerFlorianF,
pubmed-author:HorstmannSonjaS,
pubmed-author:KloiberStefanS,
pubmed-author:KohliMartin AMA,
pubmed-author:LucaeSusanneS,
pubmed-author:Müller-MyhsokBertramB,
pubmed-author:MenkeAndreasA,
pubmed-author:PfennigAndreaA,
pubmed-author:ResslerKerry JKJ,
pubmed-author:SalyakinaDariaD,
pubmed-author:UhrManfredM
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pubmed:issnType |
Electronic
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
348-59
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pubmed:meshHeading |
pubmed-meshheading:20124106-African Americans,
pubmed-meshheading:20124106-Case-Control Studies,
pubmed-meshheading:20124106-Depressive Disorder, Major,
pubmed-meshheading:20124106-Female,
pubmed-meshheading:20124106-Genetic Markers,
pubmed-meshheading:20124106-Genotype,
pubmed-meshheading:20124106-Germany,
pubmed-meshheading:20124106-Humans,
pubmed-meshheading:20124106-Linkage Disequilibrium,
pubmed-meshheading:20124106-Male,
pubmed-meshheading:20124106-Middle Aged,
pubmed-meshheading:20124106-Polymorphism, Single Nucleotide,
pubmed-meshheading:20124106-Psychiatric Status Rating Scales,
pubmed-meshheading:20124106-Receptor, trkB,
pubmed-meshheading:20124106-Regression Analysis,
pubmed-meshheading:20124106-Risk Factors,
pubmed-meshheading:20124106-Suicide, Attempted,
pubmed-meshheading:20124106-United States
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pubmed:year |
2010
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pubmed:articleTitle |
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.
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pubmed:affiliation |
Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, D-80804 Munich, Germany. kohlim@mpipsykl.mpg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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