Linked Life Data

20121711

Source:http://linkedlifedata.com/resource/pubmed/id/20121711

Statements in which the resource exists.
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pubmed-article:20121711pubmed:abstractTextThe adult subventricular zone (SVZ) contains neural stem cells that generate neuroblasts migrating to the olfactory bulb (OB) and differentiating into interneurones. The molecular cues controlling essential functions within the neurogenesis pathway such as proliferation, short and long distance migration, functional integration and cell survival are poorly understood. We have previously shown that cultured adult neural stem cells express a considerable variety of nucleotide receptors and that nucleotides and epidermal growth factor (EGF) induce converging intracellular signalling pathways that carry potential for synergism in the control of neural stem cell proliferation and cell survival. Here we investigate the role of EGF and the nucleotides ATP, ADPbetaS and UTP in neural stem cell migration.lld:pubmed
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pubmed-article:20121711pubmed:articleTitleNucleotides and epidermal growth factor induce parallel cytoskeletal rearrangements and migration in cultured adult murine neural stem cells.lld:pubmed
pubmed-article:20121711pubmed:affiliationInstitute of Cell Biology and Neuroscience, Biocenter, Goethe-University, Frankfurt, Germany.lld:pubmed
pubmed-article:20121711pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20121711pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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