Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2010-3-9
pubmed:abstractText
Successive electroacupuncture (EA) stimulation on Zusanli ST36 acupoints of rats with experimental autoimmune encephalitis (EAE), which is an inflammatory disease mediated by autoreactive T cells, relieved disease severity, inhibited specific T cell proliferation and rebuilt the CD4+ T cell subset balance. In addition, EA-treated rats had significantly higher ACTH concentrations in vivo compared to untreated EAE rats. These results indicated that EA stimulation could relieve the severity of EAE by restoring balance to the Th1/Th2/Th17/Treg Th cell subset responses by stimulating the hypothalamus to increase ACTH secretion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1872-8421
pubmed:author
pubmed:copyrightInfo
Copyright 2009 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
220
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-33
pubmed:meshHeading
pubmed-meshheading:20117842-Acupuncture Points, pubmed-meshheading:20117842-Adrenocorticotropic Hormone, pubmed-meshheading:20117842-Animals, pubmed-meshheading:20117842-Cell Count, pubmed-meshheading:20117842-Cell Proliferation, pubmed-meshheading:20117842-Chemotaxis, Leukocyte, pubmed-meshheading:20117842-Disease Models, Animal, pubmed-meshheading:20117842-Electroacupuncture, pubmed-meshheading:20117842-Encephalomyelitis, Autoimmune, Experimental, pubmed-meshheading:20117842-Female, pubmed-meshheading:20117842-Hypothalamus, pubmed-meshheading:20117842-Immune Tolerance, pubmed-meshheading:20117842-Immunosuppression, pubmed-meshheading:20117842-Lymphocyte Activation, pubmed-meshheading:20117842-Rats, pubmed-meshheading:20117842-Rats, Inbred Lew, pubmed-meshheading:20117842-T-Lymphocytes, pubmed-meshheading:20117842-T-Lymphocytes, Helper-Inducer, pubmed-meshheading:20117842-T-Lymphocytes, Regulatory, pubmed-meshheading:20117842-Th1 Cells, pubmed-meshheading:20117842-Th2 Cells, pubmed-meshheading:20117842-Treatment Outcome
pubmed:year
2010
pubmed:articleTitle
The effect of electroacupuncture on T cell responses in rats with experimental autoimmune encephalitis.
pubmed:affiliation
Department of Neurobiology, Harbin Medical University, Heilongjiang Provincial Key Laboratory of Neurobiology, 157 Bao Jian Road, Harbin 150081, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't