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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
7
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pubmed:dateCreated |
1977-10-31
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pubmed:abstractText |
1-(7-Ethylbenzofuran-2-yl)-2-tert.-butylamino-1-hydroxyethane hydrochloride (bufuralol) is a non-selective beta-adrenoceptor blocking agent which closely resembles propranolol in its properties, including potency. Bufuralol is devoid of alpha-adrenoceptor blocking activity but possesses beta-adrenoceptor agonist activity. beta-Adrenoceptor blocking activity resides mainly in the (-)-isomer though membrane stabilising properties are associated with both optical isomers.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0004-4172
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1410-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:20114-Adipose Tissue,
pubmed-meshheading:20114-Adrenergic beta-Antagonists,
pubmed-meshheading:20114-Airway Resistance,
pubmed-meshheading:20114-Anesthetics, Local,
pubmed-meshheading:20114-Animals,
pubmed-meshheading:20114-Benzofurans,
pubmed-meshheading:20114-Blood Pressure,
pubmed-meshheading:20114-Brain,
pubmed-meshheading:20114-Cats,
pubmed-meshheading:20114-Dogs,
pubmed-meshheading:20114-Drug Interactions,
pubmed-meshheading:20114-Ethanolamines,
pubmed-meshheading:20114-Gastrointestinal Motility,
pubmed-meshheading:20114-Glycogen,
pubmed-meshheading:20114-Guinea Pigs,
pubmed-meshheading:20114-Heart Rate,
pubmed-meshheading:20114-Lipid Metabolism,
pubmed-meshheading:20114-Male,
pubmed-meshheading:20114-Mice,
pubmed-meshheading:20114-Ouabain,
pubmed-meshheading:20114-Rabbits,
pubmed-meshheading:20114-Rats,
pubmed-meshheading:20114-Receptors, Adrenergic, beta,
pubmed-meshheading:20114-Refractory Period, Electrophysiological,
pubmed-meshheading:20114-Species Specificity,
pubmed-meshheading:20114-Sympathetic Nervous System,
pubmed-meshheading:20114-Vasomotor System
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pubmed:year |
1977
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pubmed:articleTitle |
Bufuralol, a new beta-adrenoceptor blocking agent in a series of benzofuran-2-ethanolamines. Part 2: pharmacology.
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pubmed:publicationType |
Journal Article,
In Vitro
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