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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
Accelerated osteoclastic bone resorption plays a central role in the pathogenesis of osteoporosis and other bone diseases. Because identifying the molecular pathways that regulate osteoclast activity provides a key to understanding the causes of these diseases and developing new treatments, we studied the effect of adenosine A(1) receptor blockade or deletion on bone density.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-10482302,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-10500098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-10664473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-10677500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-10862779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-11470917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-11588053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-16286645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-16758142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-16783407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-17316459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-17492754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-17592115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-1934868,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-2188141,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-3455637,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-3902494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-9108485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20112380-9520411
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
534-41
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pubmed:dateRevised |
2011-7-22
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pubmed:meshHeading |
pubmed-meshheading:20112380-Adenosine A1 Receptor Antagonists,
pubmed-meshheading:20112380-Animals,
pubmed-meshheading:20112380-Bone Density,
pubmed-meshheading:20112380-Bone Resorption,
pubmed-meshheading:20112380-Disease Models, Animal,
pubmed-meshheading:20112380-Female,
pubmed-meshheading:20112380-Mice,
pubmed-meshheading:20112380-Mice, Inbred C57BL,
pubmed-meshheading:20112380-Mice, Knockout,
pubmed-meshheading:20112380-Microscopy, Electron,
pubmed-meshheading:20112380-Osteoblasts,
pubmed-meshheading:20112380-Osteoclasts,
pubmed-meshheading:20112380-Ovariectomy,
pubmed-meshheading:20112380-Phenotype,
pubmed-meshheading:20112380-Receptor, Adenosine A1,
pubmed-meshheading:20112380-X-Ray Microtomography
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pubmed:year |
2010
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pubmed:articleTitle |
Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice.
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pubmed:affiliation |
New York University School of Medicine, New York, NY, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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