Source:http://linkedlifedata.com/resource/pubmed/id/20110512
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-2-12
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pubmed:abstractText |
An ideal material has yet to be discovered that can completely treat dentin hypersensitivity; however, calcium phosphate precipitation has exhibited potential value for the treatment of dentin hypersensitivity by the occlusion of dentinal tubules. We hypothesized that a novel mesoporous silica biomaterial (nano CaO@mesoporous silica, NCMS) containing nano-sized calcium oxide particles mixed with 30% phosphoric acid can efficiently occlude dentinal tubules and significantly reduce dentin permeability, even with the presence of pulpal pressure. This highly supersaturated Ca(2+)-and HPO(4)(2-)ion-containing NCMS paste was brushed onto dentin surfaces, and the ions diffused deeply into the dentinal tubules and formed a CaHPO(4).2H(2)O precipitation with a depth of 100 microm. The results of the dentin permeability tests showed that the novel mesoporous material exhibited a significant reduction in dentin permeability (p < 0.05), even under simulated pulpal pressure, as compared with our previously developed material, DP-bioglass, and a commercial desensitizing material, Seal & Protect.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biocompatible Materials,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Carriers,
http://linkedlifedata.com/resource/pubmed/chemical/Oxides,
http://linkedlifedata.com/resource/pubmed/chemical/Resin Cements,
http://linkedlifedata.com/resource/pubmed/chemical/Seal and Protect resin cement,
http://linkedlifedata.com/resource/pubmed/chemical/Silicon Dioxide,
http://linkedlifedata.com/resource/pubmed/chemical/lime
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1544-0591
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
236-40
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pubmed:meshHeading |
pubmed-meshheading:20110512-Analysis of Variance,
pubmed-meshheading:20110512-Biocompatible Materials,
pubmed-meshheading:20110512-Calcium Compounds,
pubmed-meshheading:20110512-Dentin,
pubmed-meshheading:20110512-Dentin Sensitivity,
pubmed-meshheading:20110512-Drug Carriers,
pubmed-meshheading:20110512-Humans,
pubmed-meshheading:20110512-Materials Testing,
pubmed-meshheading:20110512-Nanoparticles,
pubmed-meshheading:20110512-Oxides,
pubmed-meshheading:20110512-Resin Cements,
pubmed-meshheading:20110512-Rheology,
pubmed-meshheading:20110512-Silicon Dioxide
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pubmed:year |
2010
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pubmed:articleTitle |
A novel mesoporous biomaterial for treating dentin hypersensitivity.
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pubmed:affiliation |
School of Dentistry and Graduate Institute of Clinical Dentistry, National Taiwan University and National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei 10016, Taiwan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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