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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-6-21
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pubmed:abstractText |
Abnormalities in alveolar coagulation occur in idiopathic pulmonary fibrosis (IPF). Anticoagulants attenuate bleomycin-induced lung fibrosis in animals. In this study, we first examined the pharmacokinetics of inhaled heparin in healthy subjects. Second, we investigated the safety and tolerability of heparin inhalation in IPF patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
T
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1941-2703
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pubmed:author |
pubmed-author:BoedekerRolf HRH,
pubmed-author:GuentherAndreasA,
pubmed-author:HundackLukasL,
pubmed-author:KorfeiMartinaM,
pubmed-author:KrollHartmutH,
pubmed-author:MarkartPhilippP,
pubmed-author:NassRobertR,
pubmed-author:RuppertClemensC,
pubmed-author:ScheuchGerhardG,
pubmed-author:SeegerWernerW,
pubmed-author:StaehlerGerdG,
pubmed-author:WygreckaMalgorzataM
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-72
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pubmed:meshHeading |
pubmed-meshheading:20109123-Administration, Inhalation,
pubmed-meshheading:20109123-Adult,
pubmed-meshheading:20109123-Aged,
pubmed-meshheading:20109123-Anticoagulants,
pubmed-meshheading:20109123-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:20109123-Case-Control Studies,
pubmed-meshheading:20109123-Drug Administration Schedule,
pubmed-meshheading:20109123-Factor Xa,
pubmed-meshheading:20109123-Female,
pubmed-meshheading:20109123-Half-Life,
pubmed-meshheading:20109123-Heparin,
pubmed-meshheading:20109123-Humans,
pubmed-meshheading:20109123-Idiopathic Pulmonary Fibrosis,
pubmed-meshheading:20109123-Lung,
pubmed-meshheading:20109123-Male,
pubmed-meshheading:20109123-Middle Aged,
pubmed-meshheading:20109123-Partial Thromboplastin Time,
pubmed-meshheading:20109123-Pilot Projects,
pubmed-meshheading:20109123-Quality of Life,
pubmed-meshheading:20109123-Respiratory Function Tests,
pubmed-meshheading:20109123-Time Factors,
pubmed-meshheading:20109123-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis.
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pubmed:affiliation |
Department of Internal Medicine, Faculty of Medicine, Justus Liebig University, Giessen, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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