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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-3-2
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pubmed:abstractText |
A novel diagnostic immunoassay testing procedure for hepatitis B virus core antibody (anti-HBc) using homogeneous purified full-length hepatitis B virus core antigen (HBcAg) capsids obtained from Escherichia coli was compared with Abbott Architect anti-HBc chemiluminescent microparticle immunoassay (CMIA; indirect method) against a library of specimens. A monoclonal anti-HBc neutralization confirmatory assay was then used to determine the degree of discordance between specimens. The new assay was found to be superior in both sensitivity and specificity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1556-679X
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pubmed:author |
pubmed-author:AnLiL,
pubmed-author:ChenYixinY,
pubmed-author:FOXT FTF,
pubmed-author:FanJianJ,
pubmed-author:FengZ PZP,
pubmed-author:GeShengxiangS,
pubmed-author:HuangZhiyinZ,
pubmed-author:PratGG,
pubmed-author:SuZhijunZ,
pubmed-author:XiaNingshaoN,
pubmed-author:YeoAnthony E TAE,
pubmed-author:YuanQuanQ,
pubmed-author:ZhangJunJ,
pubmed-author:ZhengQinQ
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
464-9
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:20107008-Antibodies, Monoclonal,
pubmed-meshheading:20107008-Blotting, Western,
pubmed-meshheading:20107008-Capsid,
pubmed-meshheading:20107008-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:20107008-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20107008-Hepatitis B,
pubmed-meshheading:20107008-Hepatitis B Antibodies,
pubmed-meshheading:20107008-Hepatitis B Core Antigens,
pubmed-meshheading:20107008-Humans,
pubmed-meshheading:20107008-Microscopy, Electron, Transmission,
pubmed-meshheading:20107008-Sensitivity and Specificity
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pubmed:year |
2010
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pubmed:articleTitle |
Novel double-antigen sandwich immunoassay for human hepatitis B core antibody.
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pubmed:affiliation |
National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen, Fujian Province 361005, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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