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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0005773,
umls-concept:C0015695,
umls-concept:C0017262,
umls-concept:C0028756,
umls-concept:C0068707,
umls-concept:C0086045,
umls-concept:C0086418,
umls-concept:C0175630,
umls-concept:C0205217,
umls-concept:C0441889,
umls-concept:C0598783,
umls-concept:C1428933
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-22
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pubmed:abstractText |
Nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine with physiological effects on the control of glucose homeostasis as well as potentially involved in inflammation. The association of circulating NAMPT concentrations with obesity has not been clearly established. The aim of the present work was to evaluate the effect of obesity on circulating concentrations and gene expression levels of NAMPT in human peripheral blood cells (PBCs) as well as its involvement in inflammation, glucose and lipid metabolism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1590-3729
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2009 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
245-53
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pubmed:meshHeading |
pubmed-meshheading:20106640-Adiposity,
pubmed-meshheading:20106640-Adult,
pubmed-meshheading:20106640-Biopsy,
pubmed-meshheading:20106640-Blood Cells,
pubmed-meshheading:20106640-Body Mass Index,
pubmed-meshheading:20106640-Cytokines,
pubmed-meshheading:20106640-Dyslipidemias,
pubmed-meshheading:20106640-Fatty Liver,
pubmed-meshheading:20106640-Female,
pubmed-meshheading:20106640-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20106640-Humans,
pubmed-meshheading:20106640-Inflammation Mediators,
pubmed-meshheading:20106640-Intra-Abdominal Fat,
pubmed-meshheading:20106640-Lipids,
pubmed-meshheading:20106640-Liver,
pubmed-meshheading:20106640-Male,
pubmed-meshheading:20106640-Middle Aged,
pubmed-meshheading:20106640-Nicotinamide Phosphoribosyltransferase,
pubmed-meshheading:20106640-Obesity, Morbid,
pubmed-meshheading:20106640-RNA, Messenger
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pubmed:year |
2011
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pubmed:articleTitle |
Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity.
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pubmed:affiliation |
Metabolic Research Laboratory, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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